Trim63 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trim63
tripartite motif-containing 63
MGI:2447992

25 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Trim55^tm1Cpat/Trim55⁺ Trim63^tm1Glas/Trim63^tm1Glas involves: 129S1/Sv * C57BL/6	normal cardiovascular system phenotype	J:267246
Trim55^tm1Cpat/Trim55^tm1Cpat Trim63^tm1Glas/Trim63⁺ involves: 129S1/Sv * C57BL/6	normal cardiovascular system phenotype	J:267246
Trim55^tm1Cpat/Trim55^tm1Cpat Trim63^tm1Glas/Trim63^tm1Glas involves: 129S1/Sv * C57BL/6	abnormal heart echocardiography feature	J:267246
	abnormal M line morphology	J:267246
	abnormal myocardial fiber morphology	J:267246
	abnormal sarcomere morphology	J:267246
	abnormal Z line morphology	J:267246
	cardiac fibrosis	J:267246
	cardiac hypertrophy	J:267246
	congestive heart failure	J:267246
	decreased cardiac muscle contractility	J:267246
	postnatal lethality, incomplete penetrance	J:267246
	premature death	J:267246
	prenatal lethality, incomplete penetrance	J:267246
	pulmonary edema	J:267246
Trim55^tm1Slbt/Trim55^tm1Slbt Trim63^tm1Slbt/Trim63^tm1Slbt involves: 129 * C57BL/6	abnormal cardiac thrombosis	J:130921
	abnormal liver morphology	J:130921
	abnormal lung morphology	J:130921
	abnormal myocardial fiber morphology	J:130921
	abnormal myocardium layer morphology	J:130921
	abnormal Z line morphology	J:130921
	cardiac hypertrophy	J:130921
	decreased cardiac muscle contractility	J:130921
	decreased cardiac stroke volume	J:130921
	decreased total body fat amount	J:130921
	enlarged heart	J:130921
	hemorrhage	J:130921
	increased heart weight	J:130921
	increased quadriceps weight	J:130921
	postnatal lethality, incomplete penetrance	J:130921
	pulmonary edema	J:130921
	slow postnatal weight gain	J:130921

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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