Slc24a4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
MGI:2447362

15 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc24a4^m1Btlr/Slc24a4^m1Btlr C57BL/6J-Slc24a4^m1Btlr	decreased body weight	J:265124
Slc24a4^tm1.1Hazh/Slc24a4^tm1.1Hazh involves: 129S6/SvEvTac	abnormal enamel mineralization	J:202571
Slc24a4^tm1.1Hazh/Slc24a4^tm1.1Hazh involves: 129S6/SvEvTac	abnormal enamel morphology	J:202571
Slc24a4^tm1.1Hazh/Slc24a4^tm1.1Hazh involves: 129S6/SvEvTac * C57BL/6 * FVB/N	abnormal odor adaptation	J:180325
	abnormal olfactory system physiology	J:180325
	abnormal sensory neuron physiology	J:180325
	decreased body weight	J:180325
	impaired olfaction	J:180325
Slc24a4^tm1.2Hazh/Slc24a4^tm1.2Hazh Omp^tm4(cre)Mom/Omp⁺ involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6	abnormal olfactory system physiology	J:180325
	abnormal sensory neuron physiology	J:180325
	decreased body weight	J:180325
	impaired olfaction	J:180325
Slc24a4^tm1.2Hazh/Slc24a4^tm1.2Hazh Omp^tm4(cre)Mom/Omp^tm4(cre)Mom involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6	decreased body weight	J:180325
Slc24a4^{tm1b(KOMP)Wtsi}/Slc24a4⁺ C57BL/6N-Slc24a4^{tm1b(KOMP)Wtsi}/H	decreased red blood cell distribution width	J:211773
	enlarged thymus	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating fructosamine level	J:211773
	increased circulating HDL cholesterol level	J:211773
Slc24a4^{tm1b(KOMP)Wtsi}/Slc24a4^{tm1b(KOMP)Wtsi} C57BL/6N-Slc24a4^{tm1b(KOMP)Wtsi}/H	decreased prepulse inhibition	J:211773
	increased circulating alkaline phosphatase level	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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