Fbxo2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fbxo2
F-box protein 2
MGI:2446216

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fbxo2^{tm1b(EUCOMM)Wtsi}/Fbxo2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Fbxo2^{tm1b(EUCOMM)Wtsi}/Nju	decreased fasting circulating glucose level	J:211773
	decreased locomotor activity	J:211773
	decreased startle reflex	J:211773
	increased circulating glucose level	J:211773
Fbxo2^tm1Hlp/Fbxo2^tm1Hlp B6.129-Fbxo2^tm1Hlp	abnormal auditory brainstem response waveform shape	J:121568
	abnormal Claudius cell morphology	J:121568
	abnormal cochlear hair cell morphology	J:121568
	abnormal organ of Corti supporting cell morphology	J:121568
	normal behavior/neurological phenotype	J:121568
	cochlear degeneration	J:121568
	cochlear ganglion degeneration	J:121568
	cochlear hair cell degeneration	J:121568
	deafness	J:121568
	degeneration of organ of Corti supporting cells	J:121568
	increased or absent threshold for auditory brainstem response	J:121568
	increased susceptibility to age-related hearing loss	J:121568
	normal nervous system phenotype	J:121568

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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