Marveld2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Marveld2
MARVEL (membrane-associating) domain containing 2
MGI:2446166

34 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Marveld2^tm1.1Sria/Marveld2⁺ involves: 129X1/SvJ * C57BL/6J	abnormal myocardial fiber morphology	J:201580
	abnormal olfactory epithelium morphology	J:201580
	increased body weight	J:201580
Marveld2^tm1.1Sria/Marveld2^tm1.1Sria involves: 129X1/SvJ * C57BL/6J	abnormal distortion product otoacoustic emission	J:201580
	abnormal myocardial fiber morphology	J:201580
	abnormal olfactory epithelium morphology	J:201580
	abnormal organ of Corti morphology	J:201580
	abnormal salivary gland duct morphology	J:201580
	abnormal stria vascularis morphology	J:201580
	abnormal thyroid follicle morphology	J:201580
	abnormal utricular macula morphology	J:201580
	cochlear ganglion degeneration	J:201580
	cochlear hair cell degeneration	J:201580
	cochlear inner hair cell degeneration	J:201580
	cochlear outer hair cell degeneration	J:201580
	deafness	J:201580
	normal hearing/vestibular/ear phenotype	J:201580
	increased body weight	J:201580
	increased heart weight	J:201580
	increased kidney weight	J:201580
	increased liver weight	J:201580
	increased or absent threshold for auditory brainstem response	J:201580
	increased spleen weight	J:201580
	syndromic hearing loss	J:201580
	thin stria vascularis	J:201580
Marveld2^{tm1b(EUCOMM)Wtsi}/Marveld2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Marveld2^{tm1b(EUCOMM)Wtsi}/H	abnormal auditory brainstem response	J:211773
	abnormal ear morphology	J:211773
	abnormal startle reflex	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	enlarged heart	J:211773
Marveld2^tm1Sats/Marveld2^tm1Sats B6.Cg-Marveld2^tm1Sats	abnormal distortion product otoacoustic emission	J:261357
	absent pinna reflex	J:261357
	normal cardiovascular system phenotype	J:261357
	cochlear hair cell degeneration	J:261357
	cochlear inner hair cell degeneration	J:261357
	cochlear outer hair cell degeneration	J:261357
	deafness	J:261357
	normal digestive/alimentary phenotype	J:261357
	normal endocrine/exocrine gland phenotype	J:261357
	increased or absent threshold for auditory brainstem response	J:261357
	normal liver/biliary system phenotype	J:261357
	normal renal/urinary system phenotype	J:261357

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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