Fnip1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fnip1
folliculin interacting protein 1
MGI:2444668

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atg3^tm1.1Ywh/Atg3^tm1.1Ywh Fnip1^m1Btlr/Fnip1^m1Btlr Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal autophagy	J:234285
	absent B cells	J:234285
Flcn^tm1Baba/Flcn^tm1Baba Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Fnip2^tm1.1Lss/Fnip2^tm1.1Lss Tg(Cdh16-cre)91Igr/0 involves: C57BL/6 * ICR	enlarged kidney	J:220672
	polycystic kidney	J:220672
Fnip1^{Gt(RRM154)Byg}/Fnip1^{Gt(RRM154)Byg} Igh^tm2Cgn/Igh^tm2Cgn involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	absent B cells	J:189078
	absent B-2 B cells	J:189078
	decreased B-1 B cell number	J:189078
Fnip1^{Gt(RRM154)Byg}/Fnip1^{Gt(RRM154)Byg} Tg(BCL2)22Wehi/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	increased B cell number	J:189078
Fnip1^{Gt(RRM154)Byg}/Fnip1^{Gt(RRM154)Byg} Tg(IghelMD4)4Ccg/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	absent B cells	J:189078
	absent B-2 B cells	J:189078
	decreased B-1 B cell number	J:189078
	increased immature B cell number	J:189078
Fnip1^LPAB.1/Fnip1^LPAB.1 Tg(IghMyc)22Bri/0 involves: C57BL * C57BL/6J * SJL	increased B cell apoptosis	J:187318
	normal neoplasm	J:187318
Fnip1^m1Btlr/Fnip1^m1Btlr Prkag2^tm1.1Geno/Prkag2^tm1.1Geno Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129 * C57BL/6 * C57BL/6J * CBA	normal cardiovascular system phenotype	J:256296
Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Fnip2^tm1.1Lss/Fnip2^tm1.1Lss Tg(Cdh16-cre)91Igr/0 involves: C57BL/6 * ICR	abnormal mitochondrial physiology	J:220672
	enlarged kidney	J:220672
	polycystic kidney	J:220672
	postnatal lethality, complete penetrance	J:220672
Fnip1^tm1.2Baba/Fnip1⁺ Fnip2^tm1.2Lss/Fnip2^tm1.2Lss involves: C57BL/6	increased kidney tumor incidence	J:220672
Fnip1^tm1.2Baba/Fnip1^tm1.2Baba Igh^tm2Cgn/Igh^tm2Cgn involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	absent B cells	J:189078
	absent B-2 B cells	J:189078
	decreased B-1 B cell number	J:189078
Fnip1^tm1.2Baba/Fnip1^tm1.2Baba Tg(BCL2)22Wehi/0 involves: C57BL/6 * FVB/N * SJL	increased B cell number	J:189078
Fnip1^tm1.2Baba/Fnip1^tm1.2Baba Tg(IghelMD4)4Ccg/0 involves: C57BL/6 * C57BL/6J * FVB/N * SJL	absent B cells	J:189078
	absent B-2 B cells	J:189078
	decreased B-1 B cell number	J:189078
	increased immature B cell number	J:189078

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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