Pomt2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pomt2
protein-O-mannosyltransferase 2
MGI:2444430

20 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pomt2^tm1.1Hhu/Pomt2^tm1.1Hhu Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J	abnormal Ammon gyrus morphology	J:179356
	abnormal basement membrane morphology	J:179356
	abnormal Cajal-Retzius cell morphology	J:179356
	abnormal dentate gyrus morphology	J:179356
	abnormal forebrain morphology	J:179356
	abnormal hippocampus CA3 region morphology	J:179356
	abnormal hippocampus layer morphology	J:179356
	abnormal neocortex morphology	J:179356
	abnormal radial glial cell morphology	J:179356
	astrocytosis	J:179356
Pomt2^tm1.1Hhu/Pomt2^tm1.1Hhu H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * CBA/J	normal nervous system phenotype	J:179356
Pomt2^tm1.1Hhu/Pomt2^tm1.1Hhu Tg(GFAP-cre)25Mes/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * FVB/N	abnormal basement membrane morphology	J:179356
	abnormal cerebellar granule cell migration	J:179356
	abnormal cerebellum morphology	J:179356
Pomt2^tm1.2Hhu/Pomt2^tm1.2Hhu involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J	abnormal Reichert's membrane morphology	J:179356
	decreased embryo size	J:179356
	embryonic lethality during organogenesis, complete penetrance	J:179356
Pomt2^tm1Sstr/Pomt2^tm1Sstr involves: 129P2/OlaHsd	abnormal cell adhesion	J:205502
	embryonic growth arrest	J:205502
	embryonic lethality before implantation, complete penetrance	J:205502
	failure of blastocyst formation	J:205502

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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