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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Glis3
GLIS family zinc finger 3
MGI:2444289
29 phenotypes from 3 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Glis3tm1.2Chan/Glis3+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J
decreased circulating insulin level J:177082
decreased insulin secretion J:177082
Glis3tm1.2Chan/Glis3tm1.2Chan
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J
absent pancreatic alpha cells J:177082
absent pancreatic beta cells J:177082
decreased body size J:177082
decreased circulating insulin level J:177082
decreased insulin secretion J:177082
decreased pancreatic alpha cell number J:177082
decreased pancreatic beta cell number J:177082
decreased pancreatic delta cell number J:177082
decreased pancreatic epsilon cell number J:177082
dehydration J:177082
disorganized pancreatic islets J:177082
normal endocrine/exocrine gland phenotype J:177082
hyperglycemia J:177082
increased circulating glucose level J:177082
increased circulating ketone body level J:177082
postnatal growth retardation J:177082
postnatal lethality, complete penetrance J:177082
small pancreatic islets J:177082
Glis3tm1Amj/Glis3tm1Amj
involves: 129/Sv * C57BL/6
abnormal renal tubule epithelial cell primary cilium morphology J:148994
decreased birth weight J:148994
dilated renal tubules J:148994
hyperglycemia J:148994
increased circulating insulin level J:148994
increased glomerular capsule space J:148994
polycystic kidney J:148994
postnatal lethality, complete penetrance J:148994
Glis3tm1Hiha/Glis3tm1Hiha
involves: C57BL/6 * CBA
abnormal pancreas physiology J:150077
abnormal pancreatic islet morphology J:150077
decreased activity of thyroid gland J:150077
decreased pancreatic alpha cell number J:150077
decreased pancreatic beta cell number J:150077
decreased pancreatic delta cell number J:150077
impaired glucose tolerance J:150077
increased circulating glucose level J:150077
kidney cortex cysts J:150077
polycystic kidney J:150077
postnatal growth retardation J:150077
postnatal lethality, complete penetrance J:150077
small pancreatic islets J:150077

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory