Islr2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
MGI:2444277

15 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Islr2^tm1.1Ddg/Islr2^tm1.1Ddg involves: 129S6/SvEvTac	abnormal brain morphology	J:210221
	absent brain internal capsule	J:210221
	increased hippocampus pyramidal cell number	J:210221
Islr2^tm1.1Ddg/Islr2^tm1.1Ddg involves: 129S6/SvEvTac * BALB/cJ * C57BL/6	abnormal dorsal root ganglion morphology	J:154926
	abnormal motor neuron morphology	J:154926
	abnormal neurite morphology	J:154926
	abnormal neuron morphology	J:154926
	abnormal sensory capabilities/reflexes/nociception	J:154926
	decreased neuron number	J:154926
	perinatal lethality	J:154926
Islr2^tm1.1Ddg/Islr2^tm1.1Ddg Tg(Hlxb9-GFP)1Tmj/0 involves: 129S6/SvEvTac * BALB/cJ * C57BL/6 * CBA	abnormal axon morphology	J:154926
Islr2^tm1.1Ddg/Islr2^tm2.1Ddg Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * SJL	abnormal brain internal capsule morphology	J:210221
	abnormal brain morphology	J:210221
	abnormal telencephalon development	J:210221
	premature death	J:210221
Islr2^tm1.1Ddg/Islr2^tm2.1Ddg Tg(mI56i-cre,EGFP)1Kc/0 involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	abnormal brain internal capsule morphology	J:210221
	abnormal brain morphology	J:210221
	abnormal telencephalon development	J:210221
	decreased corticospinal tract size	J:210221
	premature death	J:210221

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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