Lmod3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lmod3
leiomodin 3 (fetal)
MGI:2444169

54 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lmod3^em1(IMPC)Mbp/Lmod3⁺ C57BL/6N-Lmod3^em1(IMPC)Mbp/Ucd	abnormal adrenal gland morphology	J:211773
	abnormal coat/hair pigmentation	J:211773
	abnormal eye morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	blind uterus	J:211773
	enlarged kidney	J:211773
	enlarged spleen	J:211773
	increased blood urea nitrogen level	J:211773
	increased erythrocyte cell number	J:211773
	increased hematocrit	J:211773
	increased hemoglobin content	J:211773
	small heart	J:211773
	small kidney	J:211773
Lmod3^em1(IMPC)Mbp/Lmod3^em1(IMPC)Mbp C57BL/6N-Lmod3^em1(IMPC)Mbp/Ucd	abnormal cholesterol homeostasis	J:211773
	abnormal eye morphology	J:211773
	abnormal skeletal muscle morphology	J:211773
	abnormal startle reflex	J:211773
	abnormal urinary bladder morphology	J:211773
	abnormal vocalization	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased grip strength	J:211773
	decreased lean body mass	J:211773
	decreased locomotor activity	J:211773
	decreased lymphocyte cell number	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	decreased total body fat amount	J:211773
	enlarged heart	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	enlarged urinary bladder	J:211773
	increased circulating insulin level	J:211773
	increased lean body mass	J:211773
	increased neutrophil cell number	J:211773
	increased total body fat amount	J:211773
Lmod3^em1Eno/Lmod3^em1Eno involves: C3H * C57BL/6	abnormal sarcomere morphology	J:222174
	abnormal Z line morphology	J:222174
	cachexia	J:222174
	centrally nucleated skeletal muscle fibers	J:222174
	decreased body size	J:222174
	decreased cardiac muscle contractility	J:222174
	decreased skeletal muscle fiber size	J:222174
	decreased skeletal muscle size	J:222174
	increased skeletal muscle glycogen level	J:222174
	postnatal growth retardation	J:222174
Lmod3^{Tn(pb-Act-RFP)1.1Zhu}/Lmod3^{Tn(pb-Act-RFP)1.1Zhu} involves: C57BL/6J	abnormal sarcomere morphology	J:223382
	abnormal skeletal muscle fiber morphology	J:223382
	abnormal Z line morphology	J:223382
	decreased body weight	J:223382
	decreased grip strength	J:223382
	decreased lean body mass	J:223382
	muscle weakness	J:223382
	postnatal growth retardation	J:223382
	skeletal muscle fiber atrophy	J:223382

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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