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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ddx11
DEAD/H box helicase 11
MGI:2443590
24 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ddx11cetus/Ddx11cetus
either: C3Fe.B6-Ddx11cetus or (involves: C3HeB/FeJ * C57BL/6J * CAST/Ei)
abnormal amniotic cavity morphology J:185600
abnormal embryonic tissue morphology J:185600
abnormal somite development J:185600
absent somites J:185600
decreased embryo size J:185600
decreased paraxial mesoderm size J:185600
embryonic growth arrest J:185600
embryonic lethality during organogenesis, complete penetrance J:185600
failure of chorioallantoic fusion J:185600
failure of heart looping J:185600
increased embryonic tissue cell apoptosis J:185600
kinked neural tube J:185600
open neural tube J:185600
small allantois J:185600
wavy neural tube J:185600
Ddx11cetus/Ddx11cetus
involves: C3HeB/FeJ * C57BL/6J
decreased paraxial mesoderm size J:98216
embryonic growth arrest J:98216
embryonic lethality during organogenesis, complete penetrance J:98216
Ddx11cetus/Ddx11tm1Jiml
involves: 129S/SvEv * C3HeB/FeJ * C57BL/6J
absent paraxial mesoderm J:185600
absent somites J:185600
decreased embryo size J:185600
embryonic growth arrest J:185600
kinked neural tube J:185600
Ddx11tm1Jiml/Ddx11tm1Jiml
involves: 129S/SvEv
abnormal cell cycle J:158490
abnormal embryo development J:158490
abnormal embryonic tissue physiology J:158490
absent paraxial mesoderm J:185600
absent somites J:185600
aneuploidy J:158490
decreased embryo size J:185600
decreased inner cell mass proliferation J:158490
embryonic growth arrest J:185600
embryonic growth retardation J:158490
embryonic lethality during organogenesis, complete penetrance J:158490
failure of chorioallantoic fusion J:158490
increased allantois apoptosis J:158490
increased embryonic tissue cell apoptosis J:158490, J:185600
kinked neural tube J:185600
placental labyrinth hypoplasia J:158490

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory