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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mylk3
myosin light chain kinase 3
MGI:2443063
23 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mylk3tm1.1Hkas/Mylk3tm1.1Hkas
involves: 129 * C57BL/6 * FVB/N
abnormal heart electrocardiography waveform feature J:210147
abnormal heart left ventricle morphology J:210147
abnormal heart left ventricle pressure J:210147
abnormal heart morphology J:210147
abnormal myocardial fiber physiology J:210147
abnormal response to exercise J:210147
congestive heart failure J:210147
decreased cardiac muscle contractility J:210147
enlarged heart J:210147
enlarged myocardial fiber J:210147
increased heart weight J:210147
increased response of heart to induced stress J:210147
increased sensitivity to induced morbidity/mortality J:210147
prolonged QRS complex duration J:210147
thin interventricular septum J:210147
Mylk3tm1.1Jtst/Mylk3tm1.1Jtst
involves: 129S/SvEv * C57BL/6
normal cardiovascular system phenotype J:167590
Mylk3tm1Jtst/Mylk3+
involves: 129S/SvEv * C57BL/6
cardiac muscle necrosis J:167590
decreased cardiac muscle contractility J:167590
enlarged myocardial fiber J:167590
increased heart weight J:167590
Mylk3tm1Jtst/Mylk3tm1Jtst
involves: 129S/SvEv * C57BL/6
abnormal heart left ventricle morphology J:167590
cardiac interstitial fibrosis J:167590
decreased cardiac muscle contractility J:167590
enlarged myocardial fiber J:167590
heart left ventricle hypertrophy J:167590
heart right ventricle hypertrophy J:167590
increased heart weight J:167590
increased left ventricle weight J:167590
thick interventricular septum J:167590
Tg(Myh6-Mylk3)3Hkas/0
Not Specified
decreased response of heart to induced stress J:210147

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory