Adamts18 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adamts18
ADAM metallopeptidase with thrombospondin type 1 motif 18
MGI:2442600

25 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adamts18^{tm1(KOMP)Vlcg}/Adamts18^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal branching involved in lung morphogenesis	J:280280
	abnormal kidney development	J:280280
	abnormal lung development	J:280280
	abnormal lung lobe morphology	J:280280
	abnormal lung volume	J:280280
	abnormal nephron number	J:280280
	abnormal right lung accessory lobe morphology	J:280280
	double ureter	J:280280
	enlarged kidney	J:280280
	small lung	J:280280
Adamts18^{tm1.1(KOMP)Vlcg}/Adamts18^{tm1.1(KOMP)Vlcg} C57BL/6N-Adamts18^{tm1.1(KOMP)Vlcg}/Ucd	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	increased hematocrit	J:211773
	increased mean corpuscular volume	J:211773
Adamts18^tm1.1Wzha/Adamts18^tm1.1Wzha involves: 129 * C57BL/6	abnormal eye development	J:258487
	decreased body size	J:258487
	decreased colon goblet cell number	J:258487
	decreased colon length	J:258487
	increased acute inflammation	J:258487
	increased incidence of tumors by chemical induction	J:258487
	increased physiological sensitivity to xenobiotic	J:258487
	increased susceptibility to induced colitis	J:258487
	overexpanded pulmonary alveolus	J:258487
Adamts18^tm1Zdl/Adamts18^tm1Zdl B6.129S6-Adamts18^tm1Zdl	abnormal reproductive system physiology	J:181091

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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