Arhgef4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgef4
Rho guanine nucleotide exchange factor 4
MGI:2442507

6 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apc^Min/Apc⁺ Arhgef4^tm1Taki/Arhgef4⁺ B6J.Cg-Arhgef4^tm1Taki Apc^Min	decreased intestinal adenoma incidence	J:157023
	decreased tumor growth/size	J:157023
Apc^Min/Apc⁺ Arhgef4^tm1Taki/Arhgef4^tm1Taki B6J.Cg-Arhgef4^tm1Taki Apc^Min	decreased intestinal adenoma incidence	J:157023
	decreased tumor growth/size	J:157023
Apc^Min/Apc⁺ Arhgef4^tm1Taki/Arhgef4^tm1Taki Spata13^tm1Taki/Spata13^tm1Taki B6J.Cg-Arhgef4^tm1Taki Spata13^tm1Taki Apc^Min	abnormal tumor pathology	J:157023
	abnormal tumor vascularization	J:157023
	decreased intestinal adenoma incidence	J:157023
	decreased physiological sensitivity to xenobiotic	J:157023
	decreased tumor growth/size	J:157023
Arhgef4^tm1Taki/Arhgef4^tm1Taki Spata13^tm1Taki/Spata13^tm1Taki B6J.Cg-Arhgef4^tm1Taki Spata13^tm1Taki	no abnormal phenotype detected	J:157023

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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