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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rhbdf2
rhomboid 5 homolog 2
MGI:2442473
40 phenotypes from 10 alleles in 14 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rhbdf2cub/Rhbdf2cub
B6.Cg-Rhbdf2cub
abnormal dermal layer morphology J:82006
abnormal hair follicle inner root sheath morphology J:82006
abnormal hair follicle morphology J:244160, J:250259
abnormal hair shaft melanin granule shape J:82006
abnormal hair shaft morphology J:82006
alopecia J:82006, J:244160
enhanced wound healing J:250259
enlarged sebaceous gland J:82006, J:244160
hyperkeratosis J:244160
skin hyperplasia J:244160
thick epidermis J:82006
white adipose tissue inflammation J:82006
Rhbdf2cub/Rhbdf2cub
MRL.Cg-Rhbdf2cub
abnormal fibroblast physiology J:250259
abnormal hair follicle morphology J:250259
abnormal keratinocyte physiology J:250259
alopecia J:250259
enhanced wound healing J:250259
enlarged sebaceous gland J:250259
hyperkeratosis J:250259
skin hyperplasia J:250259
Rhbdf2em1(IMPC)Wtsi/Rhbdf2+
C57BL/6N-Rhbdf2em1(IMPC)Wtsi/Wtsi
abnormal coat appearance J:211773
abnormal vibrissa morphology J:211773
Rhbdf2em1(IMPC)Wtsi/Rhbdf2em1(IMPC)Wtsi
C57BL/6N-Rhbdf2em1(IMPC)Wtsi/Wtsi
abnormal coat appearance J:211773
abnormal hair growth J:211773
abnormal vibrissa morphology J:211773
increased circulating magnesium level J:211773
increased mean corpuscular hemoglobin J:211773
Rhbdf2em2Mvw/Rhbdf2em2Mvw
C57BL/6J-Rhbdf2em2Mvw/Mvw
abnormal hair follicle morphology J:244160
abnormal hair growth J:244160
abnormal keratinocyte physiology J:244160
enhanced wound healing J:244160
enlarged sebaceous gland J:244160
hyperkeratosis J:244160
skin hyperplasia J:244160
Rhbdf2m1Btlr/Rhbdf2m1Btlr
C57BL/6J-Rhbdf2m1Btlr
decreased tumor necrosis factor secretion J:187583
Rhbdf2m1Btlr/Rhbdf2tm1a(KOMP)Wtsi
involves: C57BL/6J * C57BL/6N
decreased tumor necrosis factor secretion J:187583
Rhbdf2M2Btlr/Rhbdf2+
C57BL/6J-Rhbdf2M2Btlr
abnormal immune system physiology J:213194
Rhbdf2M3Btlr/Rhbdf2+
C57BL/6J-Rhbdf2M3Btlr
abnormal immune system physiology J:220064
Rhbdf2M3Btlr/Rhbdf2M3Btlr
C57BL/6J-Rhbdf2M3Btlr
abnormal immune system physiology J:220064
Rhbdf2tm1.1Mfm/Rhbdf2tm1.1Mfm
B6.129S-Rhbdf2tm1.1Mfm
abnormal foot pad morphology J:244670
decreased circulating tumor necrosis factor level J:179654
decreased tumor necrosis factor secretion J:179654
thin epidermis J:244670
Rhbdf2tm1a(KOMP)Wtsi/Rhbdf2tm1a(KOMP)Wtsi
involves: C57BL/6N
decreased tumor necrosis factor secretion J:187583
Rhbdf2tm1Mak/Rhbdf2tm1Mak
B6.129P2-Rhbdf2tm1Mak
abnormal B cell physiology J:179653
abnormal immune serum protein physiology J:179653
abnormal liver physiology J:179653
decreased circulating tumor necrosis factor level J:179653
decreased susceptibility to infection induced morbidity/mortality J:179653
decreased tumor necrosis factor secretion J:179653
increased susceptibility to bacterial infection J:179653
increased susceptibility to bacterial infection induced morbidity/mortality J:179653
Rhbdf2tm1Mak/Rhbdf2tm1Mak
involves: 129P2/OlaHsd * C57BL/6
abnormal leukocyte physiology J:221411
abnormal microglial cell physiology J:221411
normal cardiovascular system phenotype J:221411
decreased tumor necrosis factor secretion J:221411
normal skeleton phenotype J:221411
normal vision/eye phenotype J:221411
Rhbdf2Uncv/Rhbdf2+
BALB/c-Uncv
sparse hair J:52604
Rhbdf2Uncv/Rhbdf2Uncv
involves: BALB/c
azoospermia J:52604
decreased litter size J:52604
enlarged sebaceous gland J:52604
hairless J:52604
slow postnatal weight gain J:52604

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory