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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Wnk1
WNK lysine deficient protein kinase 1
MGI:2442092
11 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(Wnk1)Clhu/Gt(ROSA)26Sor+
Kdrtm1(cre)Sato/Kdr+
Wnk1Gt(OST38262)Lex/Wnk1Gt(OST38262)Lex
involves: 129S1/Sv * 129S5/SvEvBrd 		abnormal embryo development J:152906
normal cardiovascular system phenotype J:152906
Gt(ROSA)26Sortm1(Wnk1)Clhu/Gt(ROSA)26Sor+
Wnk1Gt(OST38262)Lex/Wnk1Gt(OST38262)Lex
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S5/SvEvBrd * C57BL/6 * CBA 		embryonic lethality during organogenesis J:152906
Gt(ROSA)26Sortm1(Wnk1)Clhu/Gt(ROSA)26Sor+
Wnk1Gt(OST38262)Lex/Wnk1Gt(OST38262)Lex
Tg(Tek-cre)12Flv/0
involves: 129S5/SvEvBrd * C3H * C57BL/6 		abnormal embryo development J:152906
normal cardiovascular system phenotype J:152906
neonatal lethality, complete penetrance J:152906
Tg(Cdh16-Wnk1*)#Cihu/0
involves: C57BL/6 		decreased circulating potassium level J:168700
decreased systemic arterial diastolic blood pressure J:168700
decreased systemic arterial systolic blood pressure J:168700
increased circulating aldosterone level J:168700
increased circulating angiotensinogen level J:168700
increased urine potassium level J:168700
increased urine sodium level J:168700
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory