C5ar2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

C5ar2
complement component 5a receptor 2
MGI:2442013

17 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
C5ar2^em1(IMPC)H/C5ar2^em1(IMPC)H C57BL/6NTac-C5ar2^em1(IMPC)H/H	decreased eosinophil cell number	J:211773
	increased neutrophil cell number	J:211773
C5ar2^tm1Cge/C5ar2^tm1Cge B6.129S1-C5ar2^tm1Cge	abnormal immune cell physiology	J:104092
C5ar2^tm1Cge/C5ar2^tm1Cge B6.129S1-C5ar2^tm1Cge	increased inflammatory response	J:104092
C5ar2^tm1Gdy/C5ar2^tm1Gdy involves: 129 * C57BL/6	abnormal adipose tissue physiology	J:123294
	abnormal cellular respiration	J:123294
	abnormal fat cell morphology	J:123294
	abnormal glucose homeostasis	J:123294
	abnormal induced morbidity/mortality	J:152533
	abnormal liver morphology	J:152533
	focal hepatic necrosis	J:152533
	hepatic steatosis	J:152533
	increased circulating alanine transaminase level	J:152533
	increased circulating bilirubin level	J:152533
	increased circulating insulin level	J:123294
	increased fatty acid oxidation	J:123294
	increased food intake	J:123294

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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