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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ffar2
free fatty acid receptor 2
MGI:2441731
31 phenotypes from 6 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ffar2tm1Dgen/Ffar2tm1Dgen
involves: C57BL/6
abnormal granulocyte physiology J:153951
abnormal neutrophil physiology J:153951
impaired neutrophil chemotaxis J:153951
impaired neutrophil phagocytosis J:153951
increased sensitivity to xenobiotic induced morbidity/mortality J:153951
increased susceptibility to induced arthritis J:153951
increased susceptibility to induced colitis J:153951
increased T cell number J:153951
lung inflammation J:153951
Ffar2tm1Fmgb/Ffar2tm1Fmgb
involves: 129S/SvEv
abnormal intestine physiology J:191508
decreased circulating insulin level J:191508
normal homeostasis/metabolism phenotype J:191508
impaired glucose tolerance J:191508
Ffar2tm1Gzt/Ffar2tm1Gzt
involves: C57BL/6
normal cardiovascular system phenotype J:172798
Ffar2tm1Lex/Ffar2tm1Lex
involves: 129S/SvEvBrd * C57BL/6J
abnormal circulating free fatty acids level J:138134
Ffar2tm1Soff/Ffar2tm1Soff
B6.129-Ffar2tm1Soff
normal endocrine/exocrine gland phenotype J:227939
normal homeostasis/metabolism phenotype J:227939
increased circulating insulin level J:227939
Ffar2tm2Lex/Ffar2tm2Lex
involves: 129S7/SvEvBrd * C57BL/6
abnormal colon morphology J:157383
abnormal cytokine level J:157383
abnormal defecation J:157383
abnormal inflammatory response J:157383
abnormal neutrophil morphology J:157383
decreased body weight J:157383
decreased circulating tumor necrosis factor level J:157383
decreased susceptibility to induced colitis J:157383
decreased tumor necrosis factor secretion J:157383
impaired neutrophil chemotaxis J:157383
increased body weight J:157383
increased circulating tumor necrosis factor level J:157383
increased sensitivity to xenobiotic induced morbidity/mortality J:157383
large intestinal inflammation J:157383
rectal hemorrhage J:157383
sepsis J:157383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory