Trpv5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trpv5
transient receptor potential cation channel, subfamily V, member 5
MGI:2429764

28 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trpv5^Hcalc1/Trpv5⁺ involves: C3H/HeH * C57BL/6J	abnormal kidney morphology	J:196612
	abnormal renal tubule epithelium morphology	J:196612
	abnormal renal tubule morphology	J:196612
	dilated renal tubule	J:196612
	normal homeostasis/metabolism phenotype	J:196612
	increased renal tubule apoptosis	J:196612
	increased urine calcium level	J:196612
	kidney inflammation	J:196612
	renal interstitial fibrosis	J:196612
	small kidney	J:196612
Trpv5^Hcalc1/Trpv5^Hcalc1 involves: C3H/HeH * C57BL/6J	abnormal bone structure	J:196612
	abnormal kidney morphology	J:196612
	abnormal renal tubule epithelium morphology	J:196612
	abnormal renal tubule morphology	J:196612
	abnormal vitamin D level	J:196612
	decreased circulating calcium level	J:196612
	decreased circulating phosphate level	J:196612
	decreased trabecular bone thickness	J:196612
	decreased urine pH	J:196612
	dilated renal tubule	J:196612
	normal homeostasis/metabolism phenotype	J:196612
	increased renal tubule apoptosis	J:196612
	increased urine calcium level	J:196612
	increased urine phosphate level	J:196612
	kidney inflammation	J:196612
	polydipsia	J:196612
	polyuria	J:196612
	renal interstitial fibrosis	J:196612
	small kidney	J:196612
Trpv5^m1Btlr/Trpv5^m1Btlr C57BL/6J-Trpv5^m1Btlr	diarrhea	J:192586
	increased susceptibility to induced colitis	J:192586
	intestinal inflammation	J:192586
	polydipsia	J:192586
	polyuria	J:192586
	weight loss	J:192586
Trpv5^tm1Bind/Trpv5^tm1Bind involves: 129 * C57BL/6	abnormal bone structure	J:86949
	abnormal calcium ion homeostasis	J:86949
	abnormal long bone diaphysis morphology	J:86949
	abnormal renal calcium reabsorption	J:86949
	abnormal vitamin D level	J:86949
	decreased compact bone thickness	J:86949
	decreased trabecular bone thickness	J:86949
	decreased urine pH	J:86949
	normal homeostasis/metabolism phenotype	J:86949
	increased osteoclast cell number	J:86949
	increased urine calcium level	J:86949
	increased urine phosphate level	J:86949
	polyuria	J:86949

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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