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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Card14
caspase recruitment domain family, member 14
MGI:2386258
21 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Card14em1Tshu/Card14em1Tshu
C57BL/6-Card14em1Tshu 		decreased susceptibility to chemically induced skin inflammation J:289239
Card14em2Tshu/Card14+
involves: C57BL/6 		abnormal gamma-delta T cell number J:289239
acanthosis J:289239
increased alpha-beta T cell number J:289239
postnatal lethality, incomplete penetrance J:289239
psoriasis J:289239
skin inflammation J:289239
thick epidermis J:289239
Card14em3Tshu/Card14+
involves: C57BL/6 		psoriasis J:289239
skin inflammation J:289239
thick epidermis J:289239
Card14em9Lutzy/Card14+
C57BL/6J-Card14em9Lutzy/J 		abnormal blood vessel morphology J:262723
abnormal epidermal layer morphology J:262723
acanthosis J:262723
dry skin J:262723
flaky skin J:262723
hyperkeratosis J:262723
increased keratinocyte proliferation J:262723
orthokeratosis J:262723
parakeratosis J:262723
psoriasis J:262723
skin hyperplasia J:262723
skin inflammation J:262723
skin lesions J:262723
thick epidermis J:262723
Card14em9Lutzy/Card14em9Lutzy
C57BL/6J-Card14em9Lutzy/J 		decreased body size J:262723
dry skin J:262723
flaky skin J:262723
neonatal lethality, incomplete penetrance J:262723
postnatal lethality, complete penetrance J:262723
Card14tm1Lex/Card14tm1Lex
B6.129S-Card14tm1Lex 		decreased susceptibility to chemically induced skin inflammation J:253409
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory