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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
MGI:2386030
27 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Gabbr2tm1.1Stmo/Gabbr2tm1.1Stmo
involves: 129S2/SvPas * C57BL/6J
abnormal excitatory postsynaptic currents J:205570
abnormal hippocampus CA1 region morphology J:205570
abnormal hippocampus physiology J:205570
abnormal long term spatial reference memory J:205570
abnormal synapse morphology J:205570
abnormal synaptic plasticity J:205570
impaired contextual conditioning behavior J:205570
Gabbr2tm1Arca/Gabbr2tm1Arca
involves: 129P2/OlaHsd
abnormal inhibitory postsynaptic currents J:146953
abnormal inhibitory postsynaptic potential J:146953
decreased body weight J:146953
premature death J:146953
seizures J:146953
tonic-clonic seizures J:146953
Gabbr2tm1Bet/Gabbr2+
BALB/c-Gabbr2tm1Bet
abnormal emotion/affect behavior J:103534
Gabbr2tm1Bet/Gabbr2tm1Bet
BALB/c-Gabbr2tm1Bet
abnormal brain wave pattern J:103989
abnormal depression-related behavior J:103534
abnormal emotion/affect behavior J:103989
abnormal excitatory postsynaptic currents J:103989
abnormal inhibitory postsynaptic currents J:103989
abnormal nervous system electrophysiology J:103989
abnormal synaptic transmission J:103534
abnormal touch/ nociception J:103989
clonic seizures J:103989
decreased physiological sensitivity to xenobiotic J:103989
decreased thermal nociceptive threshold J:103989
hyperactivity J:103989
hyperresponsive to tactile stimuli J:103989
impaired behavioral response to xenobiotic J:103989
impaired passive avoidance behavior J:103989
increased anxiety-related response J:103534

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory