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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cnot3
CCR4-NOT transcription complex, subunit 3
MGI:2385261
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atg5tm1Myok/Atg5tm1Myok
Cnot3tm1.1Kjkb/Cnot3tm1.1Kjkb
Tg(Ckmm-cre)5Khn/0
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * FVB 		abnormal autophagosome formation J:260012
decreased cardiac muscle contractility J:260012
increased heart weight J:260012
premature death J:260012
prolonged QT interval J:260012
Atg7tm1Tchi/Atg7tm1Tchi
Cnot3tm1.1Kjkb/Cnot3tm1.1Kjkb
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj * FVB/N 		decreased cardiac muscle contractility J:260012
premature death J:260012
Atg7tm1Tchi/Atg7tm1Tchi
Cnot3tm1.1Kjkb/Cnot3tm1.1Kjkb
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cfTg(Myh6-cre/Esr1*)1Jmk
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj * FVB/N 		decreased cardiac muscle contractility J:260012
Atg7tm1Tchi/Atg7tm1Tchi
Cnot3tm1.1Kjkb/Cnot3tm1.1Kjkb
Tg(Ckmm-cre)5Khn/0
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj * FVB 		abnormal autophagosome formation J:260012
normal cardiovascular system phenotype J:260012
premature death J:260012
Cnot3tm1.1Tya/Cnot3+
Lepob/Lepob
involves: 129P2/OlaHsd * C57BL/6J 		normal behavior/neurological phenotype J:180033
decreased body weight J:180033
decreased respiratory quotient J:180033
improved glucose tolerance J:180033
increased insulin sensitivity J:180033
increased oxygen consumption J:180033
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory