Micu1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Micu1
mitochondrial calcium uptake 1
MGI:2384909

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Micu1^em#Fink/Micu1^em#Fink C57BL/6N-Micu1^em#Fink	abnormal brain development	J:238984
	abnormal cerebellum development	J:238984
	abnormal mitochondrial morphology	J:238984
	abnormal mitochondrial physiology	J:238984
	abnormal muscle physiology	J:238984
	abnormal Purkinje cell dendrite morphology	J:238984
	ataxia	J:238984
	decreased B cell number	J:238984
	decreased birth body size	J:238984
	decreased follicular B cell number	J:238984
	decreased grip strength	J:238984
	decreased skeletal muscle fiber number	J:238984
	impaired coordination	J:238984
	increased B cell apoptosis	J:238984
	increased circulating lactate level	J:238984
	oxidative stress	J:238984
	postnatal lethality, incomplete penetrance	J:238984
Micu1^tm1bNarl/Micu1⁺ C57BL/6N-Micu1^tm1bNarl/Narl	increased total body fat amount	J:211773
Micu1^tm1bNarl/Micu1⁺ C57BL/6N-Micu1^tm1bNarl/Narl	long tibia	J:211773
Micu1^tm1bNarl/Micu1^tm1bNarl C57BL/6N-Micu1^tm1bNarl/Narl	abnormal gait	J:211773
	abnormal locomotor behavior	J:211773
	abnormal snout morphology	J:211773
	abnormal tail length	J:211773
	enlarged spleen	J:211773
	enlarged testis	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	small seminal vesicle	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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