Il23r Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il23r
interleukin 23 receptor
MGI:2181693

11 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il23r^tm1.1Kuch/Il23r^tm1.1Kuch involves: C57BL/6	abnormal CD4-positive, alpha-beta T cell physiology	J:151907
Il23r^tm1.1Kuch/Il23r^tm1.1Kuch involves: C57BL/6	decreased interleukin-9 secretion	J:151907
Il23r^tm1.1Ngh/Il23r^tm1.1Ngh involves: C57BL/6	abnormal circulating interleukin level	J:216867
	decreased physiological sensitivity to xenobiotic	J:216867
	decreased susceptibility to induced colitis	J:216867
	increased circulating interleukin-17 level	J:216867
Il23r^tm1Dnax/Il23r^tm1Dnax C57BL/6-Il23r^tm1Dnax	abnormal response/metabolism to endogenous compounds	J:124591
Il23r^tm1Dnax/Il23r^tm1Dnax C57BL/6-Il23r^tm1Dnax	normal immune system phenotype	J:111568
Il23r^tm1Kuch/Il23r^tm1Kuch C57BL/6-Il23r^tm1Kuch	abnormal CD4-positive T cell differentiation	J:148248
	abnormal CD4-positive, alpha-beta T cell physiology	J:148248
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:148248
Il23r^{tm2a(EUCOMM)Wtsi}/Il23r^{tm2a(EUCOMM)Wtsi} C57BL/6N-Il23r^{tm2a(EUCOMM)Wtsi}/Wtsi	increased circulating alanine transaminase level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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