Bbc3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bbc3
BCL2 binding component 3
MGI:2181667

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bbc3^tm1Ast/Bbc3^tm1Ast C57BL/6-Bbc3^tm1Ast	decreased cellular sensitivity to gamma-irradiation	J:86466
Bbc3^tm1Ast/Bbc3^tm1Ast C57BL/6-Bbc3^tm1Ast	decreased sensitivity to induced cell death	J:86466
Bbc3^tm1Ast/Bbc3^tm1Ast involves: C57BL/6 * NZB	abnormal CD8-positive, alpha-beta T cell physiology	J:132819
	abnormal neuron physiology	J:127640, J:130581
	abnormal splenic cell ratio	J:132819
	normal immune system phenotype	J:132819
	increased CD8-positive, alpha-beta T cell number	J:132819
	increased leukocyte cell number	J:132819
Bbc3^tm1Gpz/Bbc3^tm1Gpz involves: 129P2/OlaHsd	abnormal cell death	J:115660
	abnormal heart left ventricle pressure	J:116287
	abnormal nervous system physiology	J:115660
	decreased apoptosis	J:116287
	decreased cellular sensitivity to gamma-irradiation	J:115660
	decreased lactate dehydrogenase level	J:116287
	decreased myocardial infarct size	J:116287
	normal hematopoietic system phenotype	J:141545
	increased left ventricle developed pressure	J:116287

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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