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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lgi4
leucine-rich repeat LGI family, member 4
MGI:2180197
30 phenotypes from 4 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lgi4clp/Lgi4clp
C57BL/6J-Lgi4clp/J
abnormal axon morphology J:11392
abnormal digit morphology J:24743
abnormal forelimb morphology J:11392, J:24743
abnormal hindlimb morphology J:11392
abnormal limb morphology J:11392, J:105260
abnormal locomotor behavior J:11392
abnormal long bone morphology J:11392
abnormal maternal nurturing J:11392
abnormal myelin sheath morphology J:11392, J:24743
abnormal myelination J:11392, J:24743, J:105260
abnormal nervous system morphology J:11392, J:105260
abnormal posture J:11392, J:24743, J:105260
abnormal sciatic nerve morphology J:105260
abnormal sexual interaction J:11392
decreased body size J:11392
decreased diameter of radius J:11392
decreased diameter of ulna J:11392
impaired righting response J:11392
normal muscle phenotype J:11392
postnatal lethality, incomplete penetrance J:11392
Lgi4clp/Lgi4clp
involves: C57BL/6J
demyelination J:158973
Lgi4clp/Lgi4clp
involves: C57BL/6J * FVB/N
abnormal myelination J:208847
Lgi4tm1.1(KOMP)Vlcg/Lgi4+
C57BL/6N-Lgi4tm1.1(KOMP)Vlcg/Ucd
abnormal behavior J:211773
Lgi4tm1.1(KOMP)Vlcg/Lgi4tm1.1(KOMP)Vlcg
C57BL/6N-Lgi4tm1.1(KOMP)Vlcg/Ucd
preweaning lethality, complete penetrance J:211773
Lgi4tm1.1Jrb/Lgi4tm1.1Jrb
H2afvTg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
demyelination J:158973
Lgi4tm1.1Jrb/Lgi4tm1.1Jrb
Tg(Dhh-cre)1Mejr/0
involves: 129S4/SvJaeSor * FVB/N
demyelination J:158973
Lgi4tm1Sjm/Lgi4tm1Sjm
involves: C57BL/6 * SJL
abnormal forelimb morphology J:166449
abnormal glial cell morphology J:166449
abnormal glial cell physiology J:166449
abnormal PNS glial cell morphology J:166449
abnormal Schwann cell morphology J:166449
abnormal sciatic nerve morphology J:166449
decreased body size J:166449
decreased body weight J:166449
demyelination J:166449
neonatal lethality, incomplete penetrance J:166449
postnatal growth retardation J:166449

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory