Tlr8 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tlr8
toll-like receptor 8
MGI:2176887

18 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Tlr8^tm1Vlcg/Tlr8^tm1Vlcg B6.129S1-Tlr8^tm1Vlcg	abnormal spleen marginal zone morphology	J:165267
	decreased B-1a cell number	J:165267
	decreased B-1b cell number	J:165267
	decreased dendritic cell number	J:165267
	decreased IgG1 level	J:165267
	decreased marginal zone B cell number	J:165267
	enlarged spleen	J:165267
	glomerulonephritis	J:165267
	increased anti-double stranded DNA antibody level	J:165267
	increased anti-nuclear antigen antibody level	J:165267
	increased B-2 B cell number	J:165267
	increased circulating interleukin-12 level	J:165267
	increased IgG2a level	J:165267
	increased IgG level	J:165267
	increased IgM level	J:165267
	increased interleukin-6 secretion	J:165267
	increased spleen weight	J:165267
	renal glomerular immunoglobulin deposits	J:165267

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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