Pja2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pja2
praja ring finger ubiquitin ligase 2
MGI:2159342

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pja2^tm1.2Afel/Pja2^tm1.2Afel involves: 129S6/SvEvTac * C57BL/6J	abnormal glomerular capillary morphology	J:345592
	abnormal kidney vasculature morphology	J:345592
	abnormal mesangial matrix morphology	J:345592
	decreased body weight	J:345592
	dilated renal tubule	J:345592
	edema	J:345592
	hydronephrosis	J:345592
	increased glomerular capsule space	J:345592
	increased mesangial cell number	J:345592
	increased necroptotic process	J:345592
	kidney cortex atrophy	J:345592
	kidney inflammation	J:345592
	renal glomerulus atrophy	J:345592
Pja2^{tm1b(EUCOMM)Wtsi}/Pja2⁺ C57BL/6N-Pja2^{tm1b(EUCOMM)Wtsi}/Bay	abnormal spleen morphology	J:211773
Pja2^{tm1b(EUCOMM)Wtsi}/Pja2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Pja2^{tm1b(EUCOMM)Wtsi}/Bay	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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