Cln6 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cln6
ceroid-lipofuscinosis, neuronal 6
MGI:2159324

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cln6^nclf/Cln6^nclf B6.Cg-Cln6^nclf/J	abnormal nervous system morphology	J:211608
Cln6^nclf/Cln6^nclf involves: C57BL/6J * C57BL/10J * C3HeB/FeJLe	abnormal myelination	J:47292
	abnormal neuron physiology	J:47292
	astrocytosis	J:47292
	axon degeneration	J:47292
	hindlimb paresis	J:47292
	increased susceptibility to age-related retinal degeneration	J:47292
	paralysis	J:47292
	premature death	J:47292
	seizures	J:47292
Cln6^{tm1b(EUCOMM)Hmgu}/Cln6^{tm1b(EUCOMM)Hmgu} C57BL/6N-Cln6^{tm1b(EUCOMM)Hmgu}/Tcp	abnormal retina morphology	J:211773
	decreased prepulse inhibition	J:211773
	decreased total body fat amount	J:211773
	impaired glucose tolerance	J:211773
	increased heart weight	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23