Dppa4 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dppa4
developmental pluripotency associated 4
MGI:2157525

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dppa2^tm1.1Yam/Dppa2^tm1.1Yam Dppa4^tm1.1Yam/Dppa4^tm1.1Yam involves: 129S4/SvJae * FVB/N	abnormal lung morphology	J:178324
	abnormal pulmonary alveolus morphology	J:178324
	decreased birth weight	J:178324
	perinatal lethality, incomplete penetrance	J:178324
	preweaning lethality, incomplete penetrance	J:178324
	normal reproductive system phenotype	J:178324
Dppa2^tm1.1Yam/Dppa2^tm1.1Yam Dppa4^tm1.2Yam/Dppa4^tm1.2Yam involves: 129S4/SvJae * FVB/N	abnormal lung morphology	J:178324
	abnormal pulmonary alveolus morphology	J:178324
	perinatal lethality, incomplete penetrance	J:178324
	prenatal lethality, incomplete penetrance	J:178324
	preweaning lethality, complete penetrance	J:178324
Dppa2^tm1.1Yam/Dppa2^tm1.1Yam Dppa4^tm1Yam/Dppa4^tm1Yam involves: 129S4/SvJae	abnormal DNA methylation	J:178324
	cyanosis	J:178324
	decreased cell proliferation	J:178324
	neonatal lethality, incomplete penetrance	J:178324
	respiratory failure	J:178324
Dppa2^tm1.2Yam/Dppa2^tm1.2Yam Dppa4^tm1.1Yam/Dppa4^tm1.1Yam involves: 129S4/SvJae * FVB/N	abnormal lung morphology	J:178324
	decreased birth weight	J:178324
	perinatal lethality, incomplete penetrance	J:178324
	prenatal lethality, incomplete penetrance	J:178324
	preweaning lethality, incomplete penetrance	J:178324
	normal reproductive system phenotype	J:178324
	slow postnatal weight gain	J:178324
Dppa2^tm1Yam/Dppa2^tm1Yam Dppa4^tm1Yam/Dppa4^tm1Yam involves: 129S4/SvJae	no abnormal phenotype detected	J:178324
Dppa2^tm2.1Reik/Dppa2^tm2.1Reik Dppa4^tm2.1Reik/Dppa4^tm2.1Reik Tmem163^{Tg(ACTB-cre)2Mrt}/Tmem163⁺ involves: C57BL/6 * FVB/N	maternal effect	J:316936

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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