54 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nphs2tm1Antc/Nphs2tm1Antc 129-Nphs2tm1Antc	abnormal podocyte foot process morphology	J:87577
	abnormal podocyte morphology	J:87577
	abnormal renal glomerulus morphology	J:87577
	absent podocyte slit diaphragm	J:87577
	albuminuria	J:87577
	cortical renal glomerulopathies	J:87577
	decreased body size	J:87577
	dilated proximal convoluted tubule	J:87577
	expanded mesangial matrix	J:87577
	glomerular crescent	J:87577
	increased blood urea nitrogen level	J:87577
	increased circulating creatinine level	J:87577
	increased urine protein level	J:87577
	kidney failure	J:87577
	podocyte foot process effacement	J:87577
	postnatal lethality, complete penetrance	J:87577
	normal renal/urinary system phenotype	J:87577
Nphs2tm1Antc/Nphs2tm1Antc involves: 129 * C57BL/6J	abnormal glomerular capillary endothelium morphology	J:87577
	abnormal glomerular capillary morphology	J:87577
	abnormal kidney arterial blood vessel morphology	J:87577
	abnormal kidney cortex morphology	J:87577
	abnormal peritubular capillary morphology	J:87577
	abnormal podocyte foot process morphology	J:87577
	abnormal podocyte morphology	J:87577
	abnormal renal glomerular capsule morphology	J:87577
	abnormal renal glomerulus basement membrane morphology	J:87577
	abnormal renal glomerulus morphology	J:87577
	abnormal renal tubule epithelium morphology	J:87577
	absent podocyte slit diaphragm	J:87577
	albuminuria	J:87577
	cortical renal glomerulopathies	J:87577
	decreased body size	J:87577
	dilated proximal convoluted tubule	J:87577
	expanded mesangial matrix	J:87577
	increased blood urea nitrogen level	J:87577
	increased circulating creatinine level	J:87577
	increased urine protein level	J:87577
	kidney failure	J:87577
	kidney hemorrhage	J:87577
	mesangiolysis	J:87577
	podocyte foot process effacement	J:87577
	podocyte hypertrophy	J:87577
	podocyte microvillus transformation	J:87577
	postnatal lethality, complete penetrance	J:87577
	renal cast	J:87577
	renal glomerulus hypertrophy	J:87577
Nphs2tm1Antc/Nphs2tm3.1Antc Tg(CAG-cre/Esr1*)86Lbgn/0 involves: 129 * C57BL/6 * DBA	abnormal kidney morphology	J:166320
	abnormal renal glomerulus morphology	J:166320
	abnormal renal tubule morphology	J:166320
	albuminuria	J:166320
	dilated renal tubule	J:166320
	expanded mesangial matrix	J:166320
	glomerulosclerosis	J:166320
	increased blood urea nitrogen level	J:166320
	increased circulating cholesterol level	J:166320
	increased circulating creatinine level	J:166320
	increased mesangial cell number	J:166320
	increased systemic arterial systolic blood pressure	J:166320
	increased urine protein level	J:166320
	podocyte foot process effacement	J:166320
	podocyte hypertrophy	J:166320
	premature death	J:166320
	renal cast	J:166320
	renal interstitial fibrosis	J:166320
	renal tubular necrosis	J:166320
	renal tubule atrophy	J:166320
Nphs2tm2.1Antc/Nphs2tm2.1Antc involves: 129S2/SvPas * C57BL/6	abnormal glomerular capillary endothelium morphology	J:152878
	abnormal glomerular capillary morphology	J:152878
	abnormal glomerular endothelium fenestra morphology	J:152878
	abnormal podocyte morphology	J:152878
	abnormal proximal convoluted tubule morphology	J:152878
	abnormal renal tubule morphology	J:152878
	absent podocyte slit diaphragm	J:152878
	albuminuria	J:152878
	dilated glomerular capillary	J:152878
	dilated proximal convoluted tubule	J:152878
	dilated renal tubule	J:152878
	expanded mesangial matrix	J:152878
	glomerulosclerosis	J:152878
	increased blood urea nitrogen level	J:152878
	increased circulating creatinine level	J:152878
	kidney hemorrhage	J:152878
	mesangiolysis	J:152878
	perinatal lethality, incomplete penetrance	J:152878
	podocyte foot process effacement	J:152878
	postnatal lethality, complete penetrance	J:152878
	renal cast	J:152878
Nphs2tm2.1Antc/Nphs2tm3.1Antc Tg(CAG-cre/Esr1*)86Lbgn/0 involves: 129S2/SvPas * C57BL/6 * DBA	abnormal podocyte foot process morphology	J:245693
	decreased body weight	J:245693
	decreased circulating serum albumin level	J:245693
	decreased creatinine clearance	J:245693
	decreased podocyte number	J:245693
	fused podocyte foot processes	J:245693
	glomerulosclerosis	J:245693
	increased circulating cholesterol level	J:245693
	increased renal glomerulus basement membrane thickness	J:245693
	increased systemic arterial blood pressure	J:245693
	increased urine creatinine level	J:245693
	increased urine protein level	J:245693
	kidney failure	J:245693
	podocyte foot process effacement	J:245693
	premature death	J:245693
	renal interstitial fibrosis	J:245693
	renal tubule atrophy	J:245693