Elovl6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Elovl6
ELOVL fatty acid elongase 6
MGI:2156528

23 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Elovl6^{Gt(OST222498)Lex}/Elovl6^{Gt(OST222498)Lex} B6;129S5-Elovl6^{Gt(OST222498)Lex}/Orl	decreased circulating cholesterol level	J:82809
	enhanced coordination	J:82809
Elovl6^{Gt(OST222498)Lex}/Elovl6^{Gt(OST222498)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal fatty acids level	J:130031
	abnormal hepatocyte physiology	J:130031
	abnormal lipid homeostasis	J:130031
	abnormal liver morphology	J:130031
	abnormal pancreatic islet morphology	J:130031
	decreased circulating insulin level	J:130031
	decreased circulating leptin level	J:130031
	decreased fatty acid oxidation	J:130031
	embryonic lethality, incomplete penetrance	J:130031
	normal growth/size/body region phenotype	J:130031
	hepatic steatosis	J:130031
	improved glucose tolerance	J:130031
	increased insulin sensitivity	J:130031
	increased lean body mass	J:130031
Elovl6^{tm1b(EUCOMM)Hmgu}/Elovl6⁺ C57BL/6N-Elovl6^{tm1b(EUCOMM)Hmgu}/H	decreased exploration in new environment	J:211773
	increased red blood cell distribution width	J:211773
Elovl6^{tm1b(EUCOMM)Hmgu}/Elovl6^{tm1b(EUCOMM)Hmgu} C57BL/6N-Elovl6^{tm1b(EUCOMM)Hmgu}/H	increased circulating alkaline phosphatase level	J:211773
	increased circulating amylase level	J:211773
	increased circulating triglyceride level	J:211773
	limb grasping	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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