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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Il25
interleukin 25
MGI:2155888
30 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Il25tm1.1Cdon/Il25tm1.1Cdon
involves: 129S6/SvEvTac
abnormal chemokine secretion J:229778
abnormal colon morphology J:229778
abnormal interleukin secretion J:229778
decreased eosinophil cell number J:229778
decreased interleukin-1 beta secretion J:229778
decreased interleukin-4 secretion J:158594, J:229778
decreased interleukin-5 secretion J:158594, J:229778
decreased interleukin-9 secretion J:158594
decreased interleukin-13 secretion J:158594, J:229778
decreased susceptibility to bacterial infection J:229778
decreased susceptibility to induced colitis J:229778
decreased susceptibility to weight loss J:229778
decreased T-helper 2 cell number J:229778
decreased tumor necrosis factor secretion J:229778
increased susceptibility to type I hypersensitivity reaction J:158594
lung inflammation J:158594
Il25tm1Anjm/Il25tm1Anjm
involves: 129P2/OlaHsd * C57BL/6
abnormal interleukin secretion J:123748
abnormal mesenteric lymph node morphology J:123748
decreased eosinophil cell number J:123748
decreased interleukin-5 secretion J:123748
decreased interleukin-13 secretion J:123748
increased IgE level J:123748
increased susceptibility to parasitic infection J:123748
Il25tm1Cdon/Il25tm1Cdon
Tg(Vil1-cre)997Gum/0
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N * SJL
abnormal colon morphology J:229778
decreased susceptibility to induced colitis J:229778
decreased susceptibility to weight loss J:229778
Il25tm1Dart/Il25tm1Dart
C57BL/6-Il25tm1Dart
abnormal crypts of Lieberkuhn morphology J:123808
abnormal interferon level J:123808
abnormal interleukin level J:123808
abnormal intestinal goblet cell morphology J:123808
abnormal response to infection J:123808
decreased IgG2a level J:123808
increased susceptibility to parasitic infection J:123808
intestinal inflammation J:123808
Il25tm1Dart/Il25tm1Dart
involves: C57BL/6
abnormal interleukin level J:125296
increased sensitivity to induced morbidity/mortality J:125296
increased susceptibility to experimental autoimmune encephalomyelitis J:125296
increased T cell number J:125296
Il25tm1Lex/Il25tm1Lex
B6;129S5-Il25tm1Lex/Orl
increased circulating triglyceride level J:82809

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory