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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rem2
rad and gem related GTP binding protein 2
MGI:2155260
13 phenotypes from 2 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Rem2tm1a(EUCOMM)Hmgu/Rem2tm1a(EUCOMM)Hmgu
129S2.B6N-Rem2tm1a(EUCOMM)Hmgu 		abnormal action potential J:263600
abnormal CNS synaptic transmission J:263600
abnormal dendritic spine density J:263600
abnormal eye movement J:263600
abnormal miniature excitatory postsynaptic currents J:263600
abnormal visual cortex morphology J:263600
decreased CNS synapse formation J:263600
increased miniature inhibitory postsynaptic current frequency J:263600
normal mortality/aging J:263600
normal reproductive system phenotype J:263600
Rem2tm1a(EUCOMM)Hmgu/Rem2tm1a(EUCOMM)Hmgu
C57BL/6-Rem2tm1a(EUCOMM)Hmgu 		decreased litter size J:263600
decreased survivor rate J:263600
Rem2tm1c(EUCOMM)Hmgu/Rem2tm1c(EUCOMM)Hmgu
involves: 129S4/SvJaeSor * C57BL/6N 		abnormal action potential J:263600
abnormal CNS synaptic transmission J:263600
abnormal miniature excitatory postsynaptic currents J:263600
Rem2tm1c(EUCOMM)Hmgu/Rem2tm1c(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6N 		abnormal visual cortex morphology J:263600
Rem2tm1c(EUCOMM)Hmgu/Rem2tm1c(EUCOMM)Hmgu
Pvalbtm1(cre)Arbr/Pvalb+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N 		normal vision/eye phenotype J:263600
Rem2tm1c(EUCOMM)Hmgu/Rem2tm1c(EUCOMM)Hmgu
Viptm1(cre)Zjh/Vip+
involves: 129S4/SvJaeSor * C57BL/6N 		normal vision/eye phenotype J:263600
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory