Fbxl5 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fbxl5
F-box and leucine-rich repeat protein 5
MGI:2152883

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aco1^tm1.2Mwh/Aco1^tm1.2Mwh Fbxl5^{Gt(OST386421)Lex}/Fbxl5^{Gt(OST386421)Lex} involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6	prenatal lethality, complete penetrance	J:193752
Fbxl5^{Gt(OST386421)Lex}/Fbxl5^{Gt(OST386421)Lex} Ireb2^tm1.2Mwh/Ireb2^tm1.2Mwh involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6	anemia	J:193752
	normal mortality/aging	J:193752
Fbxl5^tm1Kei/Fbxl5^tm1Kei Ireb2^tm1Roua/Ireb2^tm1Roua B6.129-Fbxl5^tm1Kei Ireb2^tm1Roua	decreased circulating unsaturated transferrin level	J:176655
	decreased hematocrit	J:176655
	decreased hemoglobin content	J:176655
	decreased liver iron level	J:176655
	decreased mean corpuscular hemoglobin	J:176655
	decreased mean corpuscular hemoglobin concentration	J:176655
	decreased mean corpuscular volume	J:176655
	increased circulating iron level	J:176655
	microcytosis	J:176655
	normal mortality/aging	J:176655

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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