Creld1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Creld1
cysteine-rich with EGF-like domains 1
MGI:2152539

21 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Creld1^tm1.1Chlm/Creld1^tm1.1Chlm involves: 129S6/SvEvTac * NIH Black Swiss	abnormal craniofacial morphology	J:243757
	abnormal forebrain development	J:243757
	abnormal hindbrain development	J:243757
	abnormal midbrain development	J:243757
	absent organized vascular network	J:243757
	atrioventricular cushion hypoplasia	J:243757
	embryonic lethality during organogenesis, complete penetrance	J:243757
	increased embryonic tissue cell apoptosis	J:243757
Creld1^{tm1c(EUCOMM)Wtsi}/Creld1^{tm1c(EUCOMM)Wtsi} Nfatc1^tm1.1(cre)Bz/Nfatc1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N * SJL	no abnormal phenotype detected	J:304446
Creld1^{tm1c(EUCOMM)Wtsi}/Creld1^{tm1c(EUCOMM)Wtsi} Tg(CMV-cre)1Cgn/? involves: BALB/cJ * C57BL/6 * C57BL/6N * SJL	embryonic lethality during organogenesis, complete penetrance	J:304446
Creld1^{tm1c(EUCOMM)Wtsi}/Creld1^{tm1c(EUCOMM)Wtsi} Tg(Myh6-cre)2182Mds/0 involves: C57BL/6 * C57BL/6N * FVB/N * SJL	abnormal extracellular matrix morphology	J:304446
	abnormal heart development	J:304446
	abnormal trabecula carnea morphology	J:304446
	cardiac fibrosis	J:304446
	cardiovascular shunt	J:304446
	congestive heart failure	J:304446
	decreased body size	J:304446
	decreased body weight	J:304446
	increased heart atrium size	J:304446
	neonatal lethality, incomplete penetrance	J:304446
	postnatal lethality, complete penetrance	J:304446
	ventricle myocardium hypoplasia	J:304446
Creld1^{tm1c(EUCOMM)Wtsi}/Creld1^{tm1c(EUCOMM)Wtsi} Tg(Tek-cre)12Flv/0 involves: C3H * C57BL/6 * C57BL/6N * SJL	no abnormal phenotype detected	J:304446

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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