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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Calca
calcitonin/calcitonin-related polypeptide, alpha
MGI:2151253
29 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Calcatm1.1(cre/EGFP)Rpa/Calca+
involves: 129S6/SvEvTac * C57BL/6
abnormal excitatory postsynaptic currents J:206070
decreased food intake J:206070
Calcatm1.1(EGFP/HBEGF)Mjz/Calca+
B6.Cg-Calcatm1.1(EGFP/HBEGF)Mjz
no abnormal phenotype detected J:187267
Calcatm1Eme/Calcatm1Eme
involves: 129S6/SvEvTac * Black Swiss
decreased heart rate J:57708
decreased systemic arterial diastolic blood pressure J:57708
normal nervous system phenotype J:57708
Calcatm1Eme/Calcatm1Eme
involves: 129S6/SvEvTac * C57BL/6
abnormal auditory brainstem response J:117774
abnormal cochlear IHC afferent innervation pattern J:117774
Calcatm1Hku/Calcatm1Hku
involves: 129S6/SvEvTac * C57BL/6
abnormal sympathetic nervous system physiology J:80225
abnormal urine catecholamine level J:80225
decreased airway responsiveness J:80218
decreased heart rate variability J:80225
increased heart rate J:80225
increased mean systemic arterial blood pressure J:80225
increased systemic vascular resistance J:80225
Calcatm1Jpc/Calcatm1Jpc
involves: 129P2/OlaHsd
abnormal chemically-elicited antinociception J:68693
decreased behavioral withdrawal response J:68693
enhanced behavioral response to nicotine J:68693
increased chemical nociceptive threshold J:68693
Calcatm1Jpc/Calcatm1Jpc
involves: 129P2/OlaHsd * C57BL/6
impaired behavioral response to xenobiotic J:54422
Calcatm1Rfg/Calcatm1Rfg
involves: 129S7/SvEvBrd * C57BL/6
abnormal circulating calcium level J:80827
abnormal osteoblast physiology J:80827
abnormal trabecular bone morphology J:80827
abnormal urine homeostasis J:80827
decreased bone strength J:80827
increased bone mineral density J:80827
Calcatm1Rfg/Calcatm1Rfg
involves: Black Swiss
abnormal bone mineralization J:80827
abnormal circulating magnesium level J:80827
normal embryo phenotype J:80827

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory