Alpk3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Alpk3
alpha-kinase 3
MGI:2151224

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Alpk3^{Gt(OST149512)Lex}/Alpk3^{Gt(OST149512)Lex} involves: 129S5/SvEvBrd * C57BL/6J	abnormal heart layer morphology	J:222361
	abnormal heart left ventricle pressure	J:222361
	abnormal intercalated disk morphology	J:222361
	abnormal myocardial fiber morphology	J:222361
	abnormal myocardium layer morphology	J:222361
	cardiac hypertrophy	J:222361
	cardiomyopathy	J:222361
	decreased cardiac muscle contractility	J:222361
	decreased cardiac output	J:222361
	decreased cardiac stroke volume	J:222361
	decreased systemic arterial systolic blood pressure	J:222361
	decreased ventricle muscle contractility	J:222361
	dilated heart left ventricle	J:222361
	enlarged heart	J:222361
	increased heart weight	J:222361
	myocardium hypertrophy	J:222361
	thick interventricular septum	J:222361
	thick ventricular wall	J:222361
Alpk3^{tm1b(EUCOMM)Hmgu}/Alpk3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Alpk3^{tm1b(EUCOMM)Hmgu}/H	decreased cardiac muscle contractility	J:211773
	dilated heart left ventricle	J:211773
	enlarged heart	J:211773
	increased heart left ventricle size	J:211773
	increased heart weight	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	thick ventricular wall	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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