Ophn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ophn1
oligophrenin 1
MGI:2151070

26 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ophn1^tm1Bill/Y involves: 129S2/SvPas	abnormal aggression-related behavior	J:124943
	abnormal behavior	J:124943
	abnormal dendrite morphology	J:124943
	abnormal excitatory postsynaptic potential	J:124943
	abnormal response to novelty	J:124943
	abnormal spatial learning	J:124943
	decreased aggression towards mice	J:124943
	decreased anxiety-related response	J:124943
	dilated lateral ventricle	J:124943
	dilated third ventricle	J:124943
	hydrocephaly	J:124943
	hyperactivity	J:124943
	increased brain size	J:124943
	increased exploration in new environment	J:124943
	increased thigmotaxis	J:124943
	premature death	J:124943
	thin cerebral cortex	J:124943
Ophn1^tm2Bill/Y Not Specified	abnormal dendrite morphology	J:124943
Ophn1^Wtgr/Ophn1⁺ D2(B6)-Ophn1^Wtgr/EiGrsrJ	abnormal zigzag hair morphology	J:123336
	curly vibrissae	J:123336
	decreased body size	J:123336
	decreased litter size	J:123336
	transverse fur striping	J:123336
	waved hair	J:123336
Ophn1^Wtgr/Y D2(B6)-Ophn1^Wtgr/EiGrsrJ	asthenozoospermia	J:123336
Ophn1^Wtgr/Y D2(B6)-Ophn1^Wtgr/EiGrsrJ	preweaning lethality, incomplete penetrance	J:123336
Ophn1^Wtgr/Y involves: C57BL/6J * CAST/EiJ	normal mortality/aging	J:123336
Ophn1^Wtgr/Y involves: C57BL/6J * DBA/2J	normal mortality/aging	J:123336

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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