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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Spred1
sprouty protein with EVH-1 domain 1, related sequence
MGI:2150016
70 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Spred1em1(IMPC)Ccpcz/Spred1em1(IMPC)Ccpcz
C57BL/6N-Spred1em1(IMPC)Ccpcz/Ccpcz
abnormal auditory brainstem response J:211773
abnormal bone structure J:211773
abnormal brain morphology J:211773
abnormal cranium morphology J:211773
abnormal eye morphology J:211773
abnormal head morphology J:211773
abnormal head size J:211773
abnormal heart morphology J:211773
abnormal lymph node morphology J:211773
abnormal mandible morphology J:211773
abnormal maxilla morphology J:211773
abnormal ovary morphology J:211773
abnormal retina morphology J:211773
abnormal seminal vesicle morphology J:211773
abnormal skin coloration J:211773
abnormal skin morphology J:211773
abnormal snout morphology J:211773
abnormal spleen morphology J:211773
abnormal startle reflex J:211773
abnormal thymus morphology J:211773
abnormal tooth morphology J:211773
abnormal vertebrae morphology J:211773
abnormal vertebral arch morphology J:211773
abnormal zygomatic bone morphology J:211773
anophthalmia J:211773
decreased body weight J:211773
decreased circulating alkaline phosphatase level J:211773
decreased grip strength J:211773
decreased locomotor activity J:211773
decreased lymphocyte cell number J:211773
enlarged heart J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
fusion of vertebral arches J:211773
hydrocephaly J:211773
increased CD4-positive NK T cell number J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased circulating alanine transaminase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating potassium level J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased freezing behavior J:211773
increased memory-marker CD4-positive NK T cell number J:211773
increased neutrophil cell number J:211773
increased NK T cell number J:211773
increased spleen weight J:211773
increased thigmotaxis J:211773
small seminal vesicle J:211773
tremors J:211773
vertebral fusion J:211773
Spred1tm1.1Ayos/Spred1tm1.1Ayos
involves: 129 * C57BL/6 * SJL
normal craniofacial phenotype J:186742
increased mast cell degranulation J:186742
increased mast cell number J:186742
Spred1tm1Hiin/Spred1tm1Hiin
B6.Cg-Spred1tm1Hiin
abnormal discrimination learning J:144031
abnormal excitatory postsynaptic potential J:144031
abnormal spatial learning J:144031
abnormal spatial working memory J:144031
absent long-term depression J:144031
enhanced paired-pulse facilitation J:144031
impaired swimming J:144031
increased thigmotaxis J:144031
normal nervous system phenotype J:144031
reduced long-term potentiation J:144031
Spred1tm1Hiin/Spred1tm1Hiin
involves: C57BL/6
abnormal cytokine secretion J:95263
abnormal eosinophil physiology J:95263
decreased body weight J:95263
increased airway responsiveness J:95263
increased eosinophil cell number J:95263
kinked tail J:95263
short face J:95263

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory