Cygb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cygb
cytoglobin
MGI:2149481

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cygb^{tm1b(EUCOMM)Wtsi}/Cygb^{tm1b(EUCOMM)Wtsi} C57BL/6N-Cygb^{tm1b(EUCOMM)Wtsi}/Tcp	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal testis morphology	J:211773
	decreased circulating cholesterol level	J:211773
	decreased total body fat amount	J:211773
	enlarged heart	J:211773
	increased bone mineral content	J:211773
	increased heart weight	J:211773
	increased lean body mass	J:211773
	small testis	J:211773
Cygb^tm1Nka/Cygb⁺ B6.Cg-Cygb^tm1Nka	increased incidence of tumors by chemical induction	J:174134
Cygb^tm1Nka/Cygb⁺ B6.Cg-Cygb^tm1Nka	increased tumor growth/size	J:174134
Cygb^tm1Nka/Cygb^tm1Nka B6.Cg-Cygb^tm1Nka	abnormal liver physiology	J:174134
	abnormal tumor pathology	J:174134
	increased incidence of tumors by chemical induction	J:174134
	increased physiological sensitivity to xenobiotic	J:174134
	increased tumor growth/size	J:174134
Cygb^tm1Ppam/Cygb^tm1Ppam Tg(Myog-cre)1Eno/0 involves: 129 * C57BL/6	abnormal muscle precursor cell physiology	J:206378
	abnormal myoblast differentiation	J:206378
	decreased cell proliferation	J:206378
	impaired muscle regeneration	J:206378
	increased apoptosis	J:206378
	oxidative stress	J:206378
	skeletal muscle degeneration	J:206378

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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