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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ffar4
free fatty acid receptor 4
MGI:2147577
35 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ffar4tm1(KOMP)Vlcg/Ffar4tm1(KOMP)Vlcg
involves: C57BL/6NTac
abnormal beige fat cell physiology J:240649
abnormal brown adipose tissue physiology J:240649
abnormal brown fat cell differentiation J:240649
abnormal white adipose tissue morphology J:240649
abnormal white adipose tissue physiology J:240649
abnormal white fat cell differentation J:240649
decreased oxygen consumption J:240649
decreased physiological sensitivity to xenobiotic J:240649
impaired adaptive thermogenesis J:240649
Ffar4tm1.1Mbj/Ffar4tm1.1Mbj
involves: C57BL/6
abnormal insulin secretion J:211675
abnormal pancreatic somatostatin secretion J:211675
Ffar4tm1Gdds/Ffar4tm1Gdds
involves: 129 * C57BL/6
abnormal lipid level J:182599
decreased energy expenditure J:182599
decreased respiratory quotient J:182599
enlarged pancreatic islets J:182599
hepatic steatosis J:182599
impaired glucose tolerance J:182599
increased circulating alanine transaminase level J:182599
increased circulating cholesterol level J:182599
increased circulating glucose level J:182599
increased circulating HDL cholesterol level J:182599
increased circulating insulin level J:182599
increased circulating LDL cholesterol level J:182599
increased circulating leptin level J:182599
increased liver triglyceride level J:182599
increased liver weight J:182599
increased susceptibility to diet-induced obesity J:182599
increased total body fat amount J:182599
increased white adipose tissue amount J:182599
increased white fat cell size J:182599
insulin resistance J:182599
Ffar4tm1Lex/Ffar4tm1Lex
involves: 129S/SvEvBrd * C57BL/6 * C57BL/6J
normal homeostasis/metabolism phenotype J:200805
Ffar4tm1Sdmk/Ffar4tm1Sdmk
C57BL/6J-Ffar4tm1Sdmk
abnormal gustatory system physiology J:161517
abnormal sensory neuron physiology J:161517
abnormal taste sensitivity J:161517

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory