Tnfaip8 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnfaip8
tumor necrosis factor, alpha-induced protein 8
MGI:2147191

13 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Tnfaip8^{Gt(IST13629C1)Tigm}/Tnfaip8^{Gt(IST13629C1)Tigm} involves: C57BL/6N	abnormal colon morphology	J:223320
	normal digestive/alimentary phenotype	J:223320
	normal immune system phenotype	J:223320
	increased circulating interleukin-6 level	J:223320
	increased circulating interleukin-17 level	J:223320
	increased enterocyte apoptosis	J:223320
	increased interleukin-1 beta secretion	J:223320
	increased interleukin-6 secretion	J:223320
	increased interleukin-17 secretion	J:223320
	increased neutrophil cell number	J:223320
	increased susceptibility to induced colitis	J:223320
	increased susceptibility to weight loss	J:223320
	small spleen	J:223320

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23