Arrdc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arrdc3
arrestin domain containing 3
MGI:2145242

28 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arrdc3^{Gt(CSE151)Byg}/Arrdc3⁺ involves: 129P2/OlaHsd * C57BL/6	decreased body weight	J:179646
	decreased circulating adrenaline level	J:179646
	decreased circulating glucose level	J:179646
	hyperactivity	J:179646
	increased basal metabolism	J:179646
	increased circulating ketone body level	J:179646
	increased oxygen consumption	J:179646
Arrdc3^{Gt(CSE151)Byg}/Arrdc3^{Gt(CSE151)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal brown fat cell morphology	J:179646
	abnormal energy homeostasis	J:179646
	abnormal glucose homeostasis	J:179646
	abnormal hormone level	J:179646
	abnormal lipid homeostasis	J:179646
	decreased body length	J:179646
	decreased body weight	J:179646
	decreased circulating glucose level	J:179646
	decreased circulating insulin level	J:179646
	decreased circulating leptin level	J:179646
	decreased circulating triglyceride level	J:179646
	decreased circulating triiodothyronine level	J:179646
	decreased gonadal fat pad weight	J:179646
	decreased percent body fat/body weight	J:179646
	decreased susceptibility to age related obesity	J:179646
	decreased susceptibility to hepatic steatosis	J:179646
	decreased susceptibility to induced hypothermia	J:179646
	decreased white fat cell size	J:179646
	increased circulating ketone body level	J:179646
	increased insulin sensitivity	J:179646
	perinatal lethality, incomplete penetrance	J:179646
Arrdc3^{Gt(CSE513)Byg}/Arrdc3⁺ B6.129P2-Arrdc3^{Gt(CSE513)Byg}	decreased body size	J:195551
Arrdc3^{Gt(CSE513)Byg}/Arrdc3⁺ involves: 129P2/OlaHsd * C57BL/6	decreased body size	J:195551
Arrdc3^{Gt(CSE513)Byg}/Arrdc3^{Gt(CSE513)Byg} B6.129P2-Arrdc3^{Gt(CSE513)Byg}	decreased body size	J:195551
	decreased susceptibility to age related obesity	J:195551
	embryonic lethality, complete penetrance	J:195551
	thin skin	J:195551
Arrdc3^{Gt(CSE513)Byg}/Arrdc3^{Gt(CSE513)Byg} involves: 129P2/OlaHsd * C57BL/6	decreased body size	J:195551
	decreased susceptibility to age related obesity	J:195551
	embryonic lethality, complete penetrance	J:195551
	thin skin	J:195551

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23