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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
MGI:2143558
46 phenotypes from 6 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Chchd10em1(IMPC)H/Chchd10em1(IMPC)H
C57BL/6N-Chchd10em1(IMPC)H/H
increased blood urea nitrogen level J:211773
increased circulating creatinine level J:211773
increased circulating potassium level J:211773
increased grip strength J:211773
Chchd10em1(IMPC)Mbp/Chchd10em1(IMPC)Mbp
C57BL/6NCrl-Chchd10em1(IMPC)Mbp/Mmucd
abnormal testis morphology J:211773
increased circulating phosphate level J:211773
small testis J:211773
Chchd10em2Dpn/Chchd10em2Dpn
C57BL/6J-Chchd10em2Dpn
abnormal heart morphology J:344465
impaired coordination J:344465
Chchd10em3Dpn/Chchd10em3Dpn
C57BL/6J-Chchd10em3Dpn
abnormal heart echocardiography feature J:344465
abnormal heart morphology J:344465
abnormal mitochondrial crista morphology J:344465
abnormal mitochondrial physiology J:344465
abnormal tibialis anterior morphology J:344465
atrioventricular block J:344465
decreased body size J:344465
decreased body weight J:344465
decreased grip strength J:344465
decreased myocardial fiber mitochondrial DNA content J:344465
decreased skeletal muscle fiber size J:344465
normal homeostasis/metabolism phenotype J:344465
impaired coordination J:344465
impaired exercise endurance J:344465
myopathy J:344465
premature death J:344465
Chchd10em5Lutzy/Chchd10em5Lutzy
C57BL/6J-Chchd10em5Lutzy/J
abnormal heart ventricle morphology J:254726
abnormal respiratory electron transport chain J:254726
normal cellular phenotype J:254726
Chchd10em8Lutzy/Chchd10+
C57BL/6NJ-Chchd10em8Lutzy/J
abnormal cell nucleus morphology J:272524
abnormal dopaminergic neuron morphology J:272524
abnormal gait J:272524
abnormal mitochondrial crista morphology J:272524
abnormal mitochondrial matrix morphology J:272524
abnormal mitochondrial morphology J:272524
abnormal motor neuron morphology J:272524
abnormal neuromuscular synapse morphology J:272524
abnormal sarcomere morphology J:272524
abnormal skeletal muscle fiber morphology J:272524
abnormal vacuole morphology J:272524
cardiac interstitial fibrosis J:272524
centrally nucleated skeletal muscle fibers J:272524
decreased exploration in new environment J:272524
decreased grip strength J:272524
decreased skeletal muscle mass J:272524
impaired exercise endurance J:272524
impaired limb coordination J:272524
increased mitochondrial number J:272524
increased susceptibility to otitis media J:272524
kyphosis J:272524
limb grasping J:272524
premature death J:272524
weight loss J:272524
Chchd10em8Lutzy/Chchd10em8Lutzy
C57BL/6NJ-Chchd10em8Lutzy/J
decreased grip strength J:272524
impaired exercise endurance J:272524
premature death J:272524
weight loss J:272524

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory