Ap2s1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ap2s1
adaptor-related protein complex 2, sigma 1 subunit
MGI:2141861

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ap2s1^em1(IMPC)Tcp/Ap2s1⁺ C57BL/6NCrl-Ap2s1^em1(IMPC)Tcp/Tcp	abnormal cecum morphology	J:211773
	abnormal heart morphology	J:211773
	decreased body length	J:211773
	enlarged cecum	J:211773
	enlarged heart	J:211773
	hydrometra	J:211773
	small superior vagus ganglion	J:211773
Ap2s1^em1(IMPC)Tcp/Ap2s1^em1(IMPC)Tcp C57BL/6N-Ap2s1^em1(IMPC)Tcp/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
Ap2s1^em1(IMPC)Tcp/Ap2s1^em1(IMPC)Tcp C57BL/6NCrl-Ap2s1^em1(IMPC)Tcp/Tcp	abnormal egg cylinder morphology	J:279207
	absent head fold	J:279207
	absent primitive node	J:279207
	decreased embryo size	J:279207
	embryonic lethality prior to organogenesis	J:279207
	embryonic lethality, complete penetrance	J:279207
	failure of primitive streak formation	J:279207
	failure to gastrulate	J:279207
Ap2s1^em1(IMPC)Tcp/Ap2s1^em1(IMPC)Tcp C57BL/6NCrl-Ap2s1^em1(IMPC)Tcp/Tcp	preweaning lethality, incomplete penetrance	J:211773
Ap2s1^m3Rvt/Ap2s1^m3Rvt involves: C3H/HeH * C57BL/6J	embryonic lethality before implantation, complete penetrance	J:263143
Ap2s1^m3Rvt/Ap2s1^m3Rvt involves: C3H/HeH * C57BL/6J	embryonic lethality between implantation and placentation, complete penetrance	J:263143

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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