Ppp1r8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp1r8
protein phosphatase 1, regulatory subunit 8
MGI:2140494

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp1r8^tm1.1Itl/Ppp1r8^tm1Ave Tg(Alb1-cre)7Gsc/0 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NTac * FVB/N	abnormal bile duct morphology	J:238108
	abnormal oval cell morphology	J:238108
	abnormal oval cell physiology	J:238108
	bile duct epithelium hyperplasia	J:238108
	bile duct hyperplasia	J:238108
	bile duct proliferation	J:238108
	dilated bile duct	J:238108
	liver inflammation	J:238108
	normal liver/biliary system phenotype	J:238108
Ppp1r8^tm1Ave/Ppp1r8^tm1Ave involves: 129S1/Sv * 129X1/SvJ * Swiss	abnormal developmental patterning	J:91601
	abnormal ectoderm development	J:91601
	abnormal extraembryonic ectoderm morphology	J:91601
	abnormal extraembryonic tissue morphology	J:91601
	abnormal germ layer development	J:91601
	abnormal proamniotic cavity morphology	J:91601
	absent ectoplacental cone	J:91601
	absent mesoderm	J:91601
	absent proamniotic cavity	J:91601
	decreased embryo size	J:91601
	embryonic lethality between implantation and somite formation, complete penetrance	J:91601
	small proamniotic cavity	J:91601

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23