76 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+ Trp53bp2tm2Xlu/Trp53bp2tm2Xlu involves: 129P2/OlaHsd	abnormal kidney physiology	J:162396
Trp53bp2tm1b(EUCOMM)Hmgu/Trp53bp2+ C57BL/6N-Trp53bp2tm1b(EUCOMM)Hmgu/H	hyperactivity	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased hemoglobin content	J:211773
Trp53bp2tm1b(EUCOMM)Hmgu/Trp53bp2tm1b(EUCOMM)Hmgu C57BL/6N-Trp53bp2tm1b(EUCOMM)Hmgu/H	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Trp53bp2tm1Cdlo/Trp53bp2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cell cycle checkpoint function	J:146764
	abnormal T cell physiology	J:146764
	increased incidence of tumors by ionizing radiation induction	J:146764
	increased tumor incidence	J:146764
Trp53bp2tm1Cdlo/Trp53bp2tm1Cdlo involves: 129S1/Sv * 129X1/SvJ * C57BL/6	embryonic lethality, complete penetrance	J:146764
Trp53bp2tm1Xlu/Trp53bp2+ B6.129S6-Trp53bp2tm1Xlu	abnormal retina morphology	J:240594
	abnormal spinal cord central canal morphology	J:240594
	cleft palate	J:240594
	ventricular septal defect	J:240594
Trp53bp2tm1Xlu/Trp53bp2+ C.129S6-Trp53bp2tm1Xlu	abnormal embryonic neuroepithelium morphology	J:240594
	abnormal lateral ventricle morphology	J:240594
	hemorrhage	J:240594
	ventricular septal defect	J:240594
Trp53bp2tm1Xlu/Trp53bp2+ involves: 129S6/SvEvTac * C57BL/6J	increased hemangiosarcoma incidence	J:108701
	increased incidence of tumors by ionizing radiation induction	J:108701
	increased lymphoma incidence	J:108701
	increased rhabdomyosarcoma incidence	J:108701
	increased squamous cell carcinoma incidence	J:108701
	increased T cell derived lymphoma incidence	J:108701
	increased tumor incidence	J:108701
Trp53bp2tm1Xlu/Trp53bp2tm1Xlu B6.129S6-Trp53bp2tm1Xlu	abnormal dorsal root ganglion morphology	J:240594
	abnormal heart position or orientation	J:240594
	abnormal neural tube morphology	J:240594
	abnormal retina morphology	J:240594
	abnormal sex gland morphology	J:240594
	abnormal trigeminal nerve morphology	J:240594
	abnormal urethra morphology	J:240594
	anophthalmia	J:240594
	cleft palate	J:240594
	coloboma	J:240594
	craniorachischisis	J:240594
	ductus venosus stenosis	J:240594
	intracranial hemorrhage	J:240594
	micrognathia	J:240594
	microphthalmia	J:240594
	narrow head	J:240594
	neonatal lethality, complete penetrance	J:240594
	spina bifida	J:240594
	umbilical vein stenosis	J:240594
	ventricular septal defect	J:240594
	wavy neural tube	J:240594
Trp53bp2tm1Xlu/Trp53bp2tm1Xlu C.129S6-Trp53bp2tm1Xlu	abnormal brain morphology	J:162396
	abnormal cerebral cortex morphology	J:162396
	abnormal choroid plexus morphology	J:162396
	abnormal cortical plate morphology	J:162396
	abnormal cortical ventricular zone morphology	J:162396
	abnormal embryonic neuroepithelial cell proliferation	J:162396
	abnormal embryonic neuroepithelium morphology	J:162396
	abnormal embryonic/fetal subventricular zone morphology	J:162396
	abnormal gait	J:240594
	abnormal heart position or orientation	J:240594
	abnormal lateral ventricle morphology	J:240594
	abnormal neural tube morphology	J:240594
	abnormal neuron differentiation	J:162396
	abnormal neuronal migration	J:162396
	abnormal olfactory bulb morphology	J:240594
	abnormal pineal gland morphology	J:240594
	abnormal retina morphology	J:162396, J:240594
	abnormal spinal cord central canal morphology	J:240594
	abnormal stratification in cerebral cortex	J:162396
	absent abducens nerve	J:240594
	absent pineal gland	J:240594
	cleft palate	J:240594
	disorganized retina layers	J:162396
	ductus venosus stenosis	J:240594
	enlarged brain ventricles	J:240594
	exencephaly	J:240594
	hydrocephaly	J:162396
	intracranial hemorrhage	J:240594
	intraventricular hemorrhage	J:240594
	normal mortality/aging	J:162396
	small thymus	J:240594
	ventricular septal defect	J:240594
Trp53bp2tm1Xlu/Trp53bp2tm1Xlu involves: 129S6/SvEvTac * C57BL/6J	abnormal brain morphology	J:162396
	abnormal cortical ventricular zone morphology	J:162396
	abnormal dorsal root ganglion morphology	J:240594
	abnormal embryonic neuroepithelial cell proliferation	J:162396
	abnormal embryonic/fetal subventricular zone morphology	J:162396
	abnormal neural tube morphology	J:240594
	abnormal neuronal precursor proliferation	J:162396
	abnormal retina morphology	J:162396
	abnormal retina outer nuclear layer morphology	J:162396
	abnormal retina photoreceptor layer morphology	J:162396
	abnormal retina progenitor cell morphology	J:162396
	abnormal sex gland morphology	J:240594
	abnormal trigeminal nerve morphology	J:240594
	abnormal urethra morphology	J:240594
	cleft palate	J:240594
	craniorachischisis	J:240594
	decreased body size	J:108701, J:162396
	dilated brain ventricle	J:162396
	domed cranium	J:108701
	exencephaly	J:240594
	hydrocephaly	J:162396
	increased embryonic neuroepithelial cell proliferation	J:162396
	increased neuron apoptosis	J:162396
	increased neuronal precursor cell number	J:162396
	micrognathia	J:240594
	narrow head	J:240594
	perinatal lethality, incomplete penetrance	J:108701, J:162396
	postnatal lethality, complete penetrance	J:108701, J:162396
	spina bifida	J:240594