Stk17b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
MGI:2138162

9 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stk17b^tm1Hed/Stk17b^tm1Hed B6.129X1-Stk17b^tm1Hed	abnormal cytokine secretion	J:94685
	decreased double-positive T cell number	J:94685
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:94685
	increased CD4-positive, alpha-beta T cell number	J:94685
	increased interferon-gamma secretion	J:94685
	increased interleukin-2 secretion	J:94685
	increased memory T cell number	J:94685
	increased T cell proliferation	J:94685
	increased tumor necrosis factor secretion	J:94685
Stk17b^tm1Hed/Stk17b^tm1Hed involves: 129X1/SvJ * C57BL/6	increased T cell proliferation	J:94685

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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