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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Twsg1
twisted gastrulation BMP signaling modulator 1
MGI:2137520
31 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Bmp4tm1Blh/Bmp4+
Twsg1tm1Emdr/Twsg1tm1Emdr
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * SJL
abnormal caudal vertebrae morphology J:90398
abnormal craniofacial morphology J:90398
abnormal diencephalon morphology J:90398
abnormal forebrain morphology J:90398
abnormal lateral ganglionic eminence morphology J:90398
abnormal lens induction J:90398
abnormal mouth morphology J:90398
abnormal nose morphology J:90398
abnormal retina morphology J:90398
abnormal tail morphology J:90398
absent mandible J:90398
absent nasal septum J:90398
absent tongue J:90398
anophthalmia J:90398
holoprosencephaly J:90398
kinked tail J:90398
lowered ear position J:90398
oral atresia J:90398
short tail J:90398
single external naris J:90398
Bmp4tm2Blh/Bmp4+
Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
involves: 129S/SvEv * C57BL/6 * FVB/N
normal craniofacial phenotype J:88784
Bmpertm1Emdr/Bmper+
Twsg1tm1Emdr/Twsg1tm1Emdr
involves: 129 * C57BL/6 * SJL
prenatal lethality, incomplete penetrance J:141243
Bmpertm1Emdr/Bmpertm1Emdr
Twsg1tm1Emdr/Twsg1tm1Emdr
involves: 129 * C57BL/6 * SJL
abnormal vertebral column morphology J:141243
normal mortality/aging J:141243
normal skeleton phenotype J:141243
Chrdtm1Emdr/Chrdtm1Emdr
Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
involves: 129/Sv * C57BL/6 * FVB/N
abnormal mandible morphology J:88784
abnormal vertebral arch morphology J:88784
normal nervous system phenotype J:88784
perinatal lethality J:88784
Trp53tm1Brd/Trp53tm1Brd
Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
involves: 129S7/SvEvBrd * C57BL/6
abnormal craniofacial morphology J:173627
exencephaly J:173627
perinatal lethality, incomplete penetrance J:173627

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory