Arid4b Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arid4b
AT-rich interaction domain 4B
MGI:2137512

33 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Arid4a^tm1Alb/Arid4a^tm1Alb Arid4b^tm1Alb/Arid4b⁺ involves: 129S7/SvEvBrd	abnormal blood vessel morphology	J:141004
	abnormal bone marrow morphology	J:141004
	abnormal common myeloid progenitor cell morphology	J:141004
	abnormal definitive hematopoiesis	J:141004
	abnormal kidney vasculature morphology	J:141004
	abnormal leukopoiesis	J:141004
	abnormal lung vasculature morphology	J:141004
	abnormal myeloblast morphology/development	J:141004
	decreased B cell number	J:141004
	decreased body weight	J:141004
	decreased erythrocyte cell number	J:141004
	decreased lymphocyte cell number	J:141004
	decreased T cell number	J:141004
	enlarged liver	J:141004
	enlarged spleen	J:141004
	extramedullary hematopoiesis	J:141004
	hemophagocytosis	J:141004
	increased erythrocyte cell number	J:141004
	increased hematopoietic stem cell number	J:141004
	increased leukemia incidence	J:141004
	increased leukocyte cell number	J:141004
	increased monocyte cell number	J:141004
	increased neutrophil cell number	J:141004
	increased sarcoma incidence	J:141004
	increased T cell number	J:141004
	postnatal lethality	J:141004
	premature death	J:141004
	thrombocytopenia	J:141004
Arid4a^tm1Alb/Arid4a^tm1Alb Arid4b^tm1Alb/Arid4b⁺ involves: 129S7/SvEvBrd * C57BL/6	abnormal DNA methylation during gametogenesis	J:113402
	abnormal imprinting	J:113402
	maternal imprinting	J:113402
Arid4a^tm1Alb/Arid4a^tm1Alb Arid4b^tm1Alb/Arid4b^tm1Alb involves: 129S7/SvEvBrd * C57BL/6	perinatal lethality, complete penetrance	J:113402
Arid4b^tm1Alb/Arid4b⁺ Rr70^tm1Alb/Rr70⁺ involves: 129S7/SvEvBrd * C57BL/6	abnormal DNA methylation	J:113402
	abnormal imprinting	J:113402

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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